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Publications by MVP Scientists

            

No.  

Selected Publications:

1

Sherman MR, Saifer MGP, Perez-Ruiz F, (2007) PEG-uricase in the management of treatment-resistant gout and hyperuricemia.  Adv Drug Deliv Rev, doi:10.1016/j.addr.2007.06.011.

2

Kelly SJ, Delnomdedieu M, Oliverio MI, Williams LD, Saifer MGP, Sherman MR, Coffman TM, Johnson, GA, Hershfield MS (2001)  Diabetes insipidus in uricase-deficient mice: A model for evaluating therapy with poly(ethylene glycol)-uricase.  J Am Soc Nephrol 12:1001-1009.

3

Sherman MR, Williams LD, Saifer MGP, French JA, Kwak LW, Oppenheim JJ (1997) Conjugation of high molecular weight poly(ethylene glycol) to cytokines: Granulocyte-macrophage colony-stimulating factors as model substrates.  in: Poly(ethylene glycol) Chemistry and Biological Applications. ACS Symposium Series 680,  Harris JM, Zalipsky S, eds.,  American Chemical Society, Washington, DC, pp 155-169.

4

Saifer MGP, Williams LD, Sherman MR, French JA, Kwak LW, Oppenheim JJ (1997) Improved conjugation of cytokines using high molecular weight poly(ethylene glycol): PEG-GM-CSF as a prototype.  Polymer Preprints 38:576-577.

5

Smith RA, Balis FM, Ott KH , Elsberry DD , Sherman MR, Saifer MGP (1995)  Pharmacokinetics and tolerability of ventricularly administered superoxide dismutase in monkeys and preliminary clinical observations in familial ALS.  J Neurol Sci 129 (Suppl):13-18.

6

Saifer MGP, Somack R , Williams LD (1994)  Plasma clearance and immunologic properties of long-acting superoxide dismutase prepared using 35,000 to 120,000 dalton poly-ethylene glycol ( PEG ).  Adv Exp Med Biol 366:377-387.

7

Saifer MGP, Somack R , Williams LD (1994)  Plasma clearance and immunologic properties of long-acting superoxide dismutase prepared using 35,000-120,000 dalton poly-ethylene glycol ( PEG ).  in: Frontiers of Reactive Oxygen Species in Biology and Medicine,  Asada K, Yoshikawa T, eds., Elsevier, Amsterdam, pp 423-424.

8

Somack R, Saifer MGP, Williams LD (1991)  Preparation of long-acting superoxide dismutase using high molecular weight polyethylene glycol (41,000-72,000 daltons).  Free Radic Res Commun 12-13:553-562.

9

Maayani S , Sherman MR (1990)  Adenylate cyclase-linked 5-hydroxytryptamine receptors in the brain.  in:  Serotonin: From Cell Biology to Pharmacology and Therapeutics,  Paoletti R, Vanhoutte PM, Brunello N, Maggi FM, eds.,  Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 39-51.

10

Saifer MGP, Williams LD, Dang PH-C, Somack R , Sloan C, Miranda QR (1986) Orgotein, the drug version of bovine copper, zinc superoxide dismutase: III. Properties of injectable superoxide dismutase.  in: Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine,  Rotilio G , ed.,  Elsevier, Amsterdam , pp 493-496.

11 Sherman MR, Tuazon FB, Stevens YW, Carlino JA, Niu E-M (1986) "Defective" receptors in steroid-resistant conditions may be proteolytic artifacts.  Adv Exp Med Biol 196:23-51.

12

Gorsline J , Bradlow HL, Sherman MR (1985)  Triamcinolone acetonide 21-oic acid methyl ester:  A potent local antiinflammatory steroid without detectable systemic effects.  Endocrinology 116:263-273.

13

Sherman MR, Stevens J (1984)  Structure of mammalian steroid receptors: Evolving concepts and methodological developments.  Annu Rev Physiol 46:83-105.

14

Sherman MR, Stevens Y-W, Tuazon FB (1984)  Multiple forms and fragments of cytosolic glucocorticoid receptors from human leukemic cells and normal lymphocytes.  Cancer Res 44: 3783-3796 .

15

Sherman MR, Tuazon FB, Stevens Y-W, Niu E-M (1983)  Oligomeric steroid receptor forms and the products of their dissociation and proteolysis. in:  Steroid Hormone Receptors: Structure and Function, Proceedings of the 57th Nobel Symposium, Karlskoga, Sweden, 1983,  Eriksson H, Gustafsson J-Å, eds., Elsevier, Amsterdam, pp 3-24.

16

Sherman MR, Moran MC, Tuazon FB, Stevens Y-W (1983)  Structure, dissociation, and proteolysis of mammalian steroid receptors. Multiplicity of glucocorticoid receptor forms and proteolytic enzymes in rat liver and kidney cytosols.  J Biol Chem 258:10366-10377.

17

Miller LK, Tuazon FB, Niu E-M, Sherman MR (1981)  Human breast tumor estrogen receptor: Effects of molybdate and electrophoretic analyses.  Endocrinology 108:1369-1378.

18 Niu E-M, Neal RM, Pierce VK, Sherman MR (1981) Structural similarity of molybdate-stabilized steroidreceptors in human breast tumors, uteri and leukocytes. J Steroid Biochem 15:1-10.
19 Lee HJ, Bradlow HL, Moran MC, Sherman MR (1981) Binding of glucocorticoid 21-oic acids and esters to molybdate-stabilized hepatic receptors. J Steroid Biochem 14:1325-1335.
20 Sherman MR, Tuazon FB, Sömjen GJ (1981) Stabilization and cleavage of steroid receptors: Effects of leupeptin and molybdate on rat and kidney glucocorticoid receptors. Prog Clin Biol Res 74:321-337.

21

Sherman MR, Tuazon FB, Miller LK (1980)  Estrogen receptor cleavage and plasminogen activation by enzymes in human breast tumor cytosol.  Endocrinology 106:1715-1727.

22

Huber W, Menander-Huber KB, Saifer MGP, Williams LD (1980)  Bioavailability of superoxide dismutase: Implications for the anti-inflammatory action mechanism of orgotein.  Agents Actions (Supplement) 7:185-195.

23

Williams LD, Saifer MG, Dang PH-C, Huber W (1980)  Development of an arthus-like model of induced inflammation and its use in the antiinflammatory characterization of orgotein (bovine Cu,Zn superoxide dismutase).  in: Inflammation: Mechanism and Treatment,  Willoughby DA, Giroud JP, eds., MTP Press, Lancaster, UK, pp 149-156.

24

Huber W, Saifer MGP, Williams LD (1980)  Superoxide dismutase pharmacology and orgotein efficacy: New perspectives.  in: Developments in Biochemistry, Vol. 11B, Bannister WH, Bannister JV, eds., Elsevier, Amsterdam, pp 395-407.

25 Sherman MR, Barzilai D, Pine PR, Tuazon FB (1979) Glucocorticoid receptor cleavage by leupeptin-sensitive enzymes in rat kidney cytosol. Adv Exp Med Biol 117:357-375.
26 Sherman MR (1979) Allosteric and competitive steroid-receptor interactions. Monogr Endocrinol 12:123-133.

27

Bullock LP, Bardin CW, Sherman MR (1978)  Androgenic, antiandrogenic, and synandrogenic actions of progestins: Role of steric and allosteric interactions with androgen receptors.  Endocrinology 103:1768-1782.

28

Sherman MR, Pickering LA, Rollwagen FM, Miller LK (1978)  Mero-receptors: Proteolytic fragments of receptors containing the steroid-binding site.  Fed Proc 37:167-173.

29

Huber W, Saifer MGP (1977)  Orgotein, the drug version of bovine Cu,Zn superoxide dismutase: I. A summary account of safety and pharmacology in laboratory animals.  in: Superoxide and Superoxide Dismutases, Michelson A M, McCord J M, Fridovich I, eds., Academic Press, London, pp 517-536.

30

Huber W, Menander-Huber KB, Saifer MGP, Dang PH-C (1977)  Studies on the clinical and laboratory pharmacology of drug formulations of bovine Cu-Zn superoxide dismutases (orgotein).  in: Perspectives in Inflammation. Future Trends and Developments, Willoughby DA, Giroud J P, Velo G P, eds., University Park Press, Baltimore, pp 527-540.

31 Sherman MR, Diaz SC (1977) Mero-receptor formation from a larger subcomponent of the oviduct progesterone receptor. Ann N Y Acad Sci 286:81-86.
32 Friedman M, Williams LD (1977) A mathematical analysis of kinetics of consecutive, competitive reactions of protein amino groups. Adv Exp Med Biol 86B:299-319.

33

Sherman MR, Tuazon FB, Diaz SC, Miller LK (1976)  Multiple forms of oviduct progesterone receptors analyzed by ion exchange filtration and gel electrophoresis.  Biochemistry 15:980-989.

34 Sherman MR, Miller LK (1976) Fractionation of diverse steroid-binding proteins: Basic and clinical application. Curr Top Mol Endocrinol 4:51-67.

35

Sherman MR (1975)  Physical-chemical analysis of steroid hormone receptors.  Methods Enzymol 36:211-234.

36 Toft DO, Sherman MR (1975) Receptor identification by density gradient centrifugation. Methods Enzymol 36:156-166.

37

Miller LK, Diaz SC, Sherman MR (1975)  Steroid-receptor quantitation and characterization by electrophoresis in highly cross-linked polyacrylamide gels. Biochemistry 14: 4433-4443.

38

Sherman MR, Atienza S-BP, Shansky JR, Hoffman LM (1974)  Progesterone receptors of chick oviduct.  Steroid-binding “subunit” formed with divalent cations.  Biol Chem 249: 5351-5363 .

39

Friedman M, Williams LD, Masri MS (1974)  Reductive alkylation of proteins with aromatic aldehydes and sodium cyanoborohydride. Int J Pept Protein Res 6:183-185.

40

Friedman M, Williams LD (1973)  The reaction of ninhydrin with keratin proteins.  Anal Biochem 54:333-345.

41

O’Malley BW, Toft DO, Sherman MR (1971)  Progesterone-binding components of chick oviduct. II. Nuclear components.  J Biol Chem 246:1117-1122.

42

Sherman MR, Corvol PG, O’Malley BW (1970)  Progesterone-binding components of chick oviduct. I. Preliminary characterization of cytoplasmic components.  Biol Chem 245: 6085-6096 .

43

O’Malley BW, Sherman MR, Toft DO (1970)  Progesterone “receptors” in the cytoplasm and nucleus of chick oviduct target tissue.  Proc Natl Acad Sci USA 67:501-508.

44

Kluger R, Covitz F, Dennis E, Williams LD, Westheimer F (1969)  pH-Product and pH-rate profiles in the hydrolysis of methyl ethylene phosphate. Rate-limiting pseudorotation. J Am Chem Soc 91:6066-6072.

45 Piez KA, Sherman MR (1970) Characterization of the product formed by renaturation of alpha 1-CB2, a small peptide from collagen. Biochemistry 9:4129-4133.
46 Piez KA, Sherman MR (1970) Equilibrium and kinetics studies of the helix-coil transition in alpha 1-CB2, a small peptide from collagen. Biochemistry 9:4134-4140.

47

Rubin (Sherman) MM, Piez KA, Katchalsky A (1969)  Equilibrium mechanochemistry of collagen fibers.  Biochemistry 8: 3628-3637.

48

Changeux J-P, Rubin (Sherman) MM (1968)  Allosteric interactions in aspartate transcarbamylase. III. Interpretation of experimental data in terms of the model of Monod, Wyman and Changeux.  Biochemistry 7:553-561.

49

Rubin (Sherman) MM, Changeux J-P (1966)  On the nature of allosteric transitions: Implications of non-exclusive ligand binding.  J Mol Biol 21:265-274.

50

Rubin (Sherman) MM, Katchalsky A (1966)  Mathematics of band centrifugation: Concentration-independent sedimentation and diffusion in shallow density gradients.  Biopolymers 4:579-593.