| No. | U.S. and European Patents and Patent Applications by MVP Scientists |
| 1 | Williams LD, Hershfield M, Kelly SJ,
Saifer MGP, Sherman MR (2010). PEG-urate oxidase conjugates and use thereof.
US Patent 7,723,089 B2 |
| 2 | Sherman MR, Martinez AL, Bhaskaran SS,
Williams LD, Saifer MGS, French JA (2008) Polymer stabilized proteinases. European Patent Specification EP 1 421 175 B1; validated in 10 countries. |
| 3 | Bhaskaran SS, Sherman MR,
Saifer MGP, Williams LD (2008)
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity.
US Patent Application 2008/00058246 A1 |
| 4 | Sherman MR, Saifer MGP,
Williams LD, Hershfield MS, Kelly SJ (2008) Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates.
US Patent Application 2008/0057048 A1 |
| 5 | Williams LD, Hershfield MS, Kelly SJ,
Saifer MGP, Sherman MR (2008) PEG-urate oxidase conjugates and use thereof.
US Patent Application 2008/0031864 A1 |
| 6 | Sherman MR, Martinez AL,
Bhaskaran SS, Williams LD, Saifer MGS,
French JA (2007) Polymer conjugates of proteinases.
US Patent 7,229,810 B2 |
| 7 | Williams LD, Hershfield MS, Kelly SJ,
Saifer MGP, Sherman MR (2005) PEG-urate oxidase conjugates and use thereof.
European Patent Specification EP 1 100 542 B1; validated in 19 countries |
| 8 | Sherman MR, Saifer MGP,
Williams LD (2005). Aggregate-free protein compositions and methods of preparing same.
US Patent Application 2005/0014240 A1 |
| 9 | Sherman MR, Saifer MGP,
Williams LD
(2004). Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates.
US Patent 6,783,965 B1 |
| 10 | Bhaskaran SS, Sherman MR,
Saifer MGP, Williams LD (2004) Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity.
PCT Publication WO 2004/060300 A2; granted or allowed in 7 countries. |
| 11 | Saifer MGP, Martinez AL,
Williams LD, Sherman MR (2004) Polymer conjugates of interferon-beta with enhanced biological potency.
PCT Publication WO 2004/060299 A2; granted or allowed in 11 countries. |
| 12 | Bhaskaran SS, Sherman MR,
Saifer MGP, Williams LD (2004) Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity.
US Patent Application 2004/0136952 A1 |
| 13 | Saifer MGP, Martinez AL,
Williams LD, Sherman MR, (2004) Polymer conjugates of interferon-beta with enhanced biological potency.
US Patent Application 2004/0126361 A1 |
| 14 | Martinez AL, Sherman MR,
Saifer MGP, Williams LD (2004) Polymer conjugates with decreased antigenicity, methods of preparation and use.
US Patent Application 2004/0062746 A |
| 15 | Martinez AL, Sherman MR,
Saifer MGP, Williams LD (2004) Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof.
PCT Publication WO 04/030617 A2; granted or allowed in 14 countries. |
| 16 | Saifer MGP, Williams LD (2004) Quantitative detection of viruses by light scattering.
European Patent Specification EP 1 218 722 B1; validated in three countries. |
| 17 | Williams LD, Hershfield M, Kelly SJ,
Saifer MGP, Sherman MR (2003). PEG-urate oxidase conjugates and use thereof.
US Patent Application 2003/0166249 A1 |
| 18 | Williams LD, Hershfield M, Kelly SJ,
Saifer MGP, Sherman MR (2003). PEG-urate oxidase conjugates and use thereof.
US Patent 6,576,235 B1 |
| 19 | Sherman MR, Martinez AL, Bhaskaran SS,
Williams LD, Saifer MGP, French JA (2003) Polymer conjugates of proteinases.
US Patent Application 2003/0012777 A1 |
| 20 | Sherman MR, Martinez AL,
Bhaskaran SS, Williams LD, Saifer MGP (2003) Polymer stabilized proteinases
PCT Publication WO 03/002716 A2; granted in Europe; pending in Canada. |
| 21 | Saifer MGP, Williams LD (2003) Quantitation of viruses by light scattering.
US Patent 6,544,770 B2 |
| 22 | Saifer MGP, Williams LD (2002) Quantitation of viruses by light scattering.
US Patent Application 2002/0028439 A1 |
| 23 | Sherman MR, Saifer MGP,
Williams LD (2001) Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates.
PCT Publication WO 01/59078 A2; 16 patents granted in 15 countries. |
| 24 | Saifer MGP, Williams LD (2001) Quantitation of viruses by light scattering.
US Patent 6,316,185 B1 |
| 25 | Saifer MGP, Williams LD (2001) Quantitative Detection of Viruses by Light Scattering
PCT Publication WO 01/38852 A1; granted in Europe; pending in Japan and Canada. |
| 26 | Williams LD, Hershfield MS, Kelly SJ,
Saifer MGP, Sherman MR (2000) PEG-urate oxidase conjugates and use thereof.
PCT Publication WO 00/07629 A2; 40 patents granted in 35 countries. |
| 27 | Saifer M, Somack R, Williams LD (1995)Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols.
US Patent 5,468,478 |
| 28 | Saifer M, Somack R, Williams LD (1994) Intermediates for conjugation of polypeptides with high molecular weight polyalkylene glycols.
US Patent 5,283,317 |
| 29 | Saifer M, Somack R, Williams LD (1992)Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols.
US Patent 5,080,891 |
| 30 | Saifer M, Somack R, Williams LD (1991) Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols.
US Patent 5,006,333 issued in 24 additional countries |
| 31 | Huber W, Saifer MGP, Williams, LD (1978) N-Carbamylated orgotein.
US Patent 4,070,459; issued in seven additional countries |
| 32 | Huber W, Saifer MGP, Williams LD (1977) Alkylated orgotein.
US Patent 4,042,689; issued in seven additional countries |
| 33 | Huber W, Saifer MGP, Williams LD (1977) Esterified orgotein.
US Patent 4,022,888; issued in seven additional countries |
| 34 | Huber W, Saifer MGP, Williams LD (1977) Radioactive labeled orgotein.
US Patent 4,022,877; also issued in Canada |
| 35 | Saifer MGP, Williams LD,
Huber W (1977) Reduction of superoxide accumulation caused by smoke inhalation.
US Patent 4,022,224 |
| 36 | Huber W, Saifer MGP, Williams LD (1977) Acylated orgotein.
US Patent 4,017,605; issued in 14 additional countries |
| 37 | Huber W, Saifer MGP, Williams LD (1977) Cross-linked orgotein.
US Patent 4,009,267; issued in eight additional countries |
| 38 | Huber W, Chow S H, Saifer MGP (1974) Enzymatic treatment of protein mixtures containing orgotein
US Patent 3,806,411; issued in 25 additional countries |